Many cats with hypertrophic cardiomyopathy show no signs, particularly in the early stages. When symptoms do occur, they are often subtle and can be easy to miss. However, while in some cats the disease progresses slowly, in others, it can be quite rapid.
Common signs include lethargy, increased sleeping, or a reluctance to exercise or play. Some cats may hide more than usual or seem quieter than normal.
As the disease progresses, breathing changes may become more apparent. This can include rapid breathing, increased effort when breathing, or in more severe cases, open mouth breathing. These signs may indicate fluid build-up within or around the lungs.
One possible complication is a specific type of blood clot, called an aortic thromboembolism, which can cause sudden pain and weakness or paralysis in the back legs. Cats may cry out, be unable to stand, and have cold hind limbs.
In some cases, the first sign of HCM may be sudden collapse or sudden death.

